dengue virus

Structure

• size: 50 nm in diameter

Pathology

• etiologic agent of Dengue fever
• dengue NS1 protein

Laboratory

• dengue virus serology (at least 4 serotypes)
• dengue virus antigen
  • NS1 tests detect the non-structural protein 1 (NS1) of dengue virus
    • NS1 is secreted into the blood during a dengue infection
    • presence of NS1 in blood is consistent with acute phase dengue infection
• dengue virus RNA
• dengue + chikungunya + zika virus RNA

Comparative biology

• also occurs in monkeys & chimpanzees, generally as asymptomatic infection

More general terms

• flaviviridae
• arbovirus

Additional terms

• Dengue virus antibody in serum
• dengue virus vaccine (Dengvaxia)
• dengue; bone break fever; dandy fever; Duengero fever; 7 day fever