plasmablast

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Introduction

Slowly proliferating precursor to plasma cells formed in lymph nodes with migration to bone marrow. After entry into the bone marrow, plasmablasts stop proliferating & differentiate into plasma cells under the influence of adhesion molecules & cytokines. CD19-, CD56+, CD38+, syndecan-1+.

More general terms

References

  1. ↑ Bataille R, Harousseau JL. Multiple myeloma. N Engl J Med. 1997 Jun 5;336(23):1657-64. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/9171069
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