general anesthetic

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Introduction

A pharmaceutical agent that produces a loss of sensation associated with a loss of consciousness.

Indications

Adverse effects

  • repeated use of general anesthetics & sedatives, or use for > 3 hours, in children < 3 years of age & in women in the 3rd trimester of pregnancy could adversely affect child brain development[1]*
  • multiple surgeries or prolonged surgery under general anesthesia may negatively affect brain development in children < 3 years of age[2]

* ACOG takes issue with warning[1]

More general terms

More specific terms

References

  1. 1.0 1.1 1.2 FDA Safety Alert. Dec 14, 2016 General Anesthetic and Sedation Drugs: Drug Safety Communication
    New Warnings for Young Children and Pregnant Women. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm533195.htm
    FDA Drug Safety Communication: Dec 14, 2016 FDA review results in new warnings about using general anesthetics and sedation drugs in young children and pregnant women. http://www.fda.gov/Drugs/DrugSafety/ucm532356.htm
    American College of Obstetricians & Gynecologists. Dec 21, 2016 Practice Advisory: FDA Warnings Regarding Use of General Anesthetics and Sedation Drugs in Young Children and Pregnant Women. http://www.acog.org/About-ACOG/News-Room/Practice-Advisories/FDA-Warnings-Regarding-Use-of-General-Anesthetics-and-Sedation-Drugs
  2. 2.0 2.1 FDA Safety Alert. April 27, 2017 General Anesthetic and Sedation Drugs: Drug Safety Communication
    FDA Approves Label Changes for Use in Young Children. https://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm555631.htm