phensuximide (Milontin)

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Introduction

Tradename: Milontin.

Indications

seizures

Dosage

500-1000 mg PO BID/TID

Tabs: 500 mg

Pharmacokinetics

  • rapidly absorbed
  • metabolized in liver to active N-desmethyl derivative

elimination via liver

elimination via kidney

1/2life = 4 hours

protein binding = <5 %

elimination by hemodialysis = -

elimination by hemoperfusion = -

elimination by peritoneal dialysis = -

Adverse effects

Drug interactions

Laboratory

More general terms

References

  1. The Pharmacological Basis of Therapeutics, 8th ed. Gilman et al, eds. Permagon Press/McGraw Hill pg 450
  2. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995

Database