gallium nitrate (Ganite)

Introduction

Tradename: Ganite.

Indications

• treatment of symptomatic hypercalcemia of malignancy that has not responded to adquate hydration

Dosage

200 mg/m2 IV infusion for 5 consecutive days

Injection: 25 mg/mL (20 mL)

Adverse effects

• common (> 10%)
  • metallic taste, nausea/vomiting, diarrhea, renal toxicity, hypophosphatemia
• less common (1-10%)
  • hypocalcemia
• uncommon (< 1%)
  • anemia, optic neuritis, hearing impairment
• other
  • bone marrow toxicity

More general terms

• metabolic agent (metabolic modifier)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=61635
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=172317
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5282394
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=472092
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3029558