phenmetrazine (Oxazimedrine, Preludin, Mefolin)

Pharmacokinetics

• metabolized in liver to largely inactive metabolites
• metabolites excreted by the kidney

elimination via liver

elimination via kidney

1/2life = 8 hours

Adverse effects

• insomnia
• agitation
• nervousness
• hyperthermia
• hyperventilation
• hypertension
• convulsions

• drug adverse effects of analeptics
• drug adverse effects of psychotropic agents
• drug adverse effects of sympathomimetic(s)

Interferences

• may cause false positives in immunoassays for amphetamines in urine

Mechanism of action

• CNS stimulant
• appetite suppressant

More general terms

• adrenergic neuron stimulant
• analeptic (CNS stimulant)
• amine
• aromatic compound

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4762
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=92159