balsalazide (Colazal, Giazo)

Indications

• ulcerative colitis

Dosage

2250 mg PO TID (3 750 mg tabs TID)

Tabs: 750 mg

Adverse effects

• common: dyspepsia, headache, nausea, alopecia
• less common: interstitial nephritis, pericaridits, pancreatitis, hypersensitivity colitis

• drug adverse effects of NSAIDs

Mechanism of action

• metabolized to mesalamine in the colon

More general terms

• 5-aminosalicylate (5-ASA)

Additional terms

• mesalamine (Asacol, Rowasa, Pentasa, Pentasacaps, Lialda, Apriso, Canasa, Delzicol)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=107954
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=92726
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=54585