abarelix (Plenaxis)

Introduction

Tradename: Plenaxis

Indications

• advanced prostate cancer

Adverse effects

• allergic reactions (life-threatening) 4%
• hot flashes
• insomnia
• constipation
• gynecomastia
• mastodynia

Mechanism of action

• blocks gonadotropin-releasing hormone receptors
• does not cause initial testosterone surge like Lupron

More general terms

• antineoplastic agent (chemotherapeutic agent)