palonosetron (Aloxi)

Introduction

Tradename: Aloxi (FDA approved 2003)

Indications

• nausea/vomiting associated with chemotherapy

Dosage

oral form (Aloxi)

Adverse effects

• prolongation of the QT interval

Mechanism of action

• 5HT3 receptor antagonist

More general terms

• serotonin antagonist
• anti-emetic

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=148211
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=178148