coenzyme A [CoA] biosynthesis
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Introduction
Biochemistry
- coenzyme-A biosynthesis 1
- enzyme: pantothenate kinase
- substrate: pantothenate + ATP
- product: 4-phosphopantothenate + ADP
- coenzyme-A biosynthesis 2
- enzyme: phosphopantothenoylcysteine synthetase
- substrate: 4-phosphopantothenate + ATP + cysteine
- product: 4-phosphopantothenoylcysteine + ADP
- coenzyme-A biosynthesis 3
- coenzyme-A biosynthesis 4
- enzyme: dephospho-CoA-pyrophosphorylase
- substrate: 4-phosphopantetheine + ATP
- product: dephosphocoenzyme-A + H2P2O7=
- coenzyme-A biosynthesis 5
- enzyme: dephospho-CoA-kinase
- substrate: 4-phosphopantetheine + ATP
- product: coenzyme-A + ADP