gonadoblastoma

Epidemiology

rare

Pathology

• arises mostly in the dysgenetic gonads of phenotypic females who harbor some Y-chromosomal material
• copies of TSPY fall within the GBY critical region & TSPY1 is preferentially expressed in germ cells of tumor aggregates in gonadoblastoma

More general terms

• sex cord stromal tumor
• germ cell neoplasm

Database

• OMIM: https://mirror.omim.org/entry/424500