ITIM-like motif
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Introduction
Immunoreceptor tyrosine-based inhibitory motifs found in cytoplasmic domains of NK cell killer inhibitory receptors.
Recruit phosphatases (primarily SHP-1) upon tyrosine phosphorylation.
More general terms
Additional terms
- immunoreceptor tyrosine-based activator motif (ITAM)
- immunoreceptor tyrosine-based inhibitory motif (ITIM)