parathyroid adenomatosis [PRAD]-1 gene, CCND1 or bcl-1
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Introduction
PRAD for parathyroid adenomatosis.
Pathology
- the PRAD1 gene was originally identified as a clonally rearranged & overexpressed gene linked to the bcl-1 locus in a set of benign parathyroid tumors.
- chromosomal translocation & gene amplification of PRAD1 has also been demonstrated in:
More general terms
Additional terms
References
- ↑ Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM, Arnold A. A novel cyclin encoded by a bcl1-linked candidate oncogene. Nature. 1991 Apr 11;350(6318):512-5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/18265421
- ↑ Jiang W, Kahn SM, Tomita N, Zhang YJ, Lu SH, Weinstein IB. Amplification and expression of the human cyclin D gene in esophageal cancer. Cancer Res. 1992 May 15;52(10):2980-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1533816
- ↑ OMIM https://mirror.omim.org/entry/151400
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 506
- ↑ Hinz et al. Mol & Cell Biol 19:2690-98, 1999