hematopoietic stem cell leukemia [SCL] gene, tal1 or TCL5
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Introduction
1p32
Function
- probably encodes a hematopoietic transcription factor involved in early hematopoiesis
Pathology
- gene origionally identified at the site of a 1;14 translocation associated with a hematopoietic stem cell leukemia
More general terms
Additional terms
References
- ↑ Aplan PD, Lombardi DP, Ginsberg AM, Cossman J, Bertness VL, Kirsch IR. Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity. Science. 1990 Dec 7;250(4986):1426-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2255914
- ↑ Hunter T. Cooperation between oncogenes. Cell. 1991 Jan 25;64(2):249-70. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1988147