mllt10 gene
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Introduction
10p12
Pathology
- chromosomal translocation t(10;11)(p12;q23) involving MLLT10 with MLL/HRX is associated with acute leukemias
- result is a rogue activator protein
- chromosomal translocation t(10;11)(p13;q14) involving MLLT10 with PICALM is associated with diffuse histiocytic lymphomas
More general terms
References
- ↑ OMIM https://mirror.omim.org/entry/602409
- ↑ Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Genes/AF10.html