N-acetylserotonin O-methyltransferase-like protein (ASMTL) gene

Introduction

Xp22.3; Yp11.3

Structure

• located in the pseudoautosomal region 1 (PAR1) of chromosome X & chromosome Y
• represents a unique fusion product of 2 different genes of different evolutionary origin & function
• the N-terminus is homologous to the bacterial maf/orfE genes
• the C-terminus is homologous to ASMT
• exon duplication, exon shuffling & gene fusion seem to be common characteristics of the PAR1 region

More general terms

• unclassified gene

Database

• OMIM: https://mirror.omim.org/entry/300162
• OMIM: https://mirror.omim.org/entry/400011
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8623