lipopolysaccharide-binding protein (LBP)

Function

• binds to the lipid A moiety of bacterial lipopolysaccharide (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria
• the LBP/LPS complex seems to interact with the CD14 receptor

Structure

• belongs to the BPI/LBP/plunc superfamily, BPI/LBP family

Compartment

secreted

Laboratory

• lipopolysaccharide-binding protein in serum/plasma

More general terms

• opsonin
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3929
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3929
• OMIM: https://mirror.omim.org/entry/151990
• UniProt: http://www.uniprot.org/uniprot/P18428.html