IGF-1/IGF binding protein 3/acid-labile subunit glycoprotein

Function

• 85% of IGF-1 is bound in molecular complex with IGF-binding protein 3 & acid labile subunit glycoprotein
• this prolongs 1/2life of IGF-1 from 10 minutes to 12 hours & renders IGF-1 inactive

Structure

• ternary complex of IGF-1, IGFBP-3 & ALS

More general terms

• molecular complex
• membrane protein