XPC/hHR23B heterodimer

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[1]

Introduction

initiates global genome nucleotide excision repair by binding to lesion, distorting DNA double helix & recruiting other factors. possible role in open complex formation/stabilization. hHR23A can substitute for hHR23B in vitro.

More general terms

References

  1. ↑ de Laat WL et al, Molecular mechonisms of nucleotide excision repair. Genes & Dev 13:768-85, 1999 PMID: https://www.ncbi.nlm.nih.gov/pubmed/10197977
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