voltage-dependent Na+ channel

Function

• mediates voltage-dependent Na+ permeability of excitable membranes

Structure

• consists of:
  • pore-forming alpha subunit
  • beta-1 subunit
    • noncovalently associated with alpha subunit
  • beta-2 subunit
    • covalently linked to alpha subunit by disulfide bonds

More general terms

• molecular complex
• voltage-gated ion channel
• Na+ channel
• phosphoprotein
• plasma membrane protein

Database

• OMIM: https://mirror.omim.org/entry/182392
• OMIM: https://mirror.omim.org/entry/600235