B-raf1 proto-oncogene or B-raf proto-oncogene

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Introduction

Point mutations in B-raf gene occur in 66% of patients with melanoma[2]. These are somatic (acquired mutations). V599E found in 80% of B-raf point mutations.

More general terms

References

  1. OMIM https://mirror.omim.org/entry/164757
  2. 2.0 2.1 Journal Watch 22(16):128, 2002 Davies H et al, Nature 417:949, 2002 Pollock PM & Meltzer PS, Nature 417:906, 2002

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