sialic acid-binding Ig-like lectin 15 (siglec-15, CD33 antigen-like 3, SIGLEC15, CD33L3)

Function

• binds sialylated glycoproteins
• interacts with TYROBP & HCST

Structure

• belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
• contains 1 Ig-like C2-type domain (immunoglobulin-like)
• contains 1 Ig-like V-type domain (immunoglobulin-like)

Compartment

membrane

Expression

• expressed in macrophage &/or dendritic cells of spleen & lymph nodes

More general terms

• lectin
• membrane protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6ZMC9.html