melanoma-associated antigen 4; MAGE-4 antigen; MAGE-X2 antigen; MAGE-41 antigen; cancer/testis antigen 1.4; CT1.4 (MAGEA4, MAGE4)

Function

• unknown
• may play a role in embryonal development, tumor transformation or aspects of tumor progression

Structure

contains 1 MAGE domain

Expression

• expressed in many tumors of several types, including melanoma, head & neck squamous cell carcinoma, lung carcinoma & breast carcinoma
• not expressed in normal tissues except testes & placenta

Laboratory

• MAGE A4 Ab in serum/plasma

More general terms

• melanoma associated antigen (MAGE)

Database

• UniProt: http://www.uniprot.org/uniprot/P43358.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4103
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4103
• OMIM: https://mirror.omim.org/entry/300175