APP intracellular domain

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Introduction

C-terminal product of gamma secretase cleavage of amyloid precursor protein (APP)

More general terms

References

  1. Okochi M, Steiner H, Fukumori A, Tanii H, Tomita T, Tanaka T, Iwatsubo T, Kudo T, Takeda M, Haass C. Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. EMBO J. 2002 Oct 15;21(20):5408-16. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12374741