phospholipase DDHD2 (DDHD domain-containing protein 2, SAM, WWE & DDHD domain-containing protein 1, DDHD2, KIAA0725, SAMWD1)

Function

• phospholipase
• hydrolyzes preferentially phosphatidic acid & phosphatidylethanolamine
• role in maintenance of endoplasmic reticulum &/or Golgi

Structure

• belongs to the PA-PLA1 family
• contains 1 DDHD domain
• contains 1 SAM (sterile alpha motif) domain
• contains 1 WWE domain

Compartment

cytoplasm, ytoplasmic granule

Expression

ubiquitously expressed (at protein level)

Notes

uncertain whether Met-1 or Met-31 is the initiator

More general terms

• phospholipase

Database

• UniProt: http://www.uniprot.org/uniprot/O94830.html