nucleolar GTP-binding protein 2; autoantigen NGP-1 (GNL2, NGP1)

Function

• associates with pre-60S ribosomal subunits in the nucleolus, implicated in their matureation & nuclear export

Structure

• belongs to the MMR1/HSR1 GTP-binding protein family NOG2 subfamily
• contains 1 G (guanine nucleotide-binding) domain

Compartment

nucleus, nucleolus

Expression

• ubiquitously expressed at relatively low levels
• highest expression in testes

More general terms

• nuclear protein
• guanine nucleotide regulatory protein (GNRP)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29889
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29889
• OMIM: https://mirror.omim.org/entry/609365
• UniProt: http://www.uniprot.org/uniprot/Q13823.html