GPN-loop GTPase 1; MBD2-interacting protein; MBDin; XPA-binding protein 1 (GPN1, MBDIN, XAB1, HUSSY-23)

Function

• forms an interface between the RNA polymerase 2 enzyme & chaperone/scaffolding protein
• may be involved in nuclear localization of XPA
• tightly associated with the RNA polymerase 2 complex
• interacts with XPA

Structure

belongs to the GPN-loop GTPase family

Compartment

cytoplasm

Expression

expressed ubiquitously

More general terms

• guanine nucleotide regulatory protein (GNRP)
• phosphoprotein

Additional terms

• DNA repair protein complementing XP-A cells; xeroderma pigmentosum group A-complementing protein (XPA, XPAC)
• HUSSY protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11321
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:11321
• OMIM: https://mirror.omim.org/entry/611479
• UniProt: http://www.uniprot.org/uniprot/Q9HCN4.html