signal recognition particle receptor subunit alpha; SR-alpha; docking protein alpha; DP-alpha (SRPR)

Function

• in conjunction with SRP, ensures the correct targeting of nascent secretory proteins to the endoplasmic reticulum membrane system
• associates with beta chain (SRPRB) to form the SRP receptor

Structure

belongs to the GTP-binding SRP family

Compartment

• endoplasmic reticulum membrane
• peripheral membrane protein
• thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain

More general terms

• guanine nucleotide regulatory protein (GNRP)
• protein subunit
• phosphoprotein

Component of

• signal recognition peptide [SRP] receptor or docking protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6734
• OMIM: https://mirror.omim.org/entry/182180
• UniProt: http://www.uniprot.org/uniprot/P08240.html