signal recognition particle

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[1][2]

Introduction

SRP has the shape of a rod, 24 nm long & 5 nm wide with 7SL rRNA forming the backbone of the molecule. SRP binds nascent peptides destined for the ER/GOLGI, halts elongation & delivers intact peptide/80S elongation complex to the endoplasmic reticulum.

More general terms

Additional terms

References

  1. ↑ Bourne HR et al, The GTPase superfamily: a conserved switch for diverse cell functions Nature 348:125 1990 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2122258
  2. ↑ Stryer Biochemistry WH Freeman & Co, New York, 1988 pg 770
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