interferon-induced guanylate-binding protein 1; guanine nucleotide-binding protein 1; GTP-binding protein 1; GBP-1; HuGBP-1 (GBP1)

Function

binds GTP, GDP & GMP

Structure

belongs to the GBP family

Compartment

• cell membrane; lipid-anchor; cytoplasmic side (putative)

Expression

• induced by interferon gamma during macrophage activation

Notes

• distinguish from GTP-binding protein 1

More general terms

• guanine nucleotide regulatory protein (GNRP)
• prenyl protein

Additional terms

• GTP-binding protein 1; G-protein 1; GP-1; GP1 (GTPBP1)

Database

• UniProt: http://www.uniprot.org/uniprot/P32455.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2633
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2633
• OMIM: https://mirror.omim.org/entry/600411
• OMIM: https://mirror.omim.org/entry/139380