katanin p80 WD40-containing subunit B1 (katanin p80 subunit B1, p80 katanin, KATNB1)

Function

• component of katanin, complex which severs microtubules (ATP-dependent
• targets enzymatic subunit KATNA1 to sites of action, i.e. centrosome
• interacts with KATNA1 enhances the microtubule binding & severing activity of KATNA1

Compartment

• cytoplasm, centrosome, spindle
• localized to the interphase centrosome & mitotic spindle poles

More general terms

• enzyme regulatory subunit

Component of

• katenin

Database

• OMIM: https://mirror.omim.org/entry/602703
• UniProt: http://www.uniprot.org/uniprot/Q9BVA0.html