ribonuclease H2 subunit C (RNase H2 subunit C, ribonuclease HI subunit C, Aicardi-Goutieres syndrome 3 protein, AGS3, RNase H1 small subunit, RNASEH2C, AYP1)

Function

• non catalytic subunit of RNase H2
• T6 pseudogene located upstream of SRY on chromosome Y is derived from transcript of this gene

Structure

belongs to the Rnase H2 subunit C family

Compartment

nucleus (probable)

Alternative splicing

named isoforms=2

Expression

widely expressed

Pathology

• defects in RNASEH2A result in Aicardi-Goutieres syndrome 3

More general terms

• enzyme regulatory subunit

Component of

• ribonuclease H2 (RNase H2)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8415
• UniProt: http://www.uniprot.org/uniprot/Q8TDP1.html