phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5, PI3-kinase p101 subunit, protein FOAP-2, PIK3R5)

Function

• regulatory subunit of the PI3K gamma complex
• interacts with:
  • G beta gamma proteins
  • catalytic subunit, i.e. PI-3-kinase p110 gamma

Compartment

nucleus cytoplasm, membrane

Expression

• expressed in leukocytes > spleen, lymph node, thymus & bone marrow

More general terms

• enzyme regulatory subunit

Component of

• phosphoinositide-3-kinase (phosphatidylinositol-3-kinase, PI3K)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8WYR1.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?