uncoupling protein

Function

• mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis
• as a result, energy is dissipated in the form of heat
• may play a role in thermoregulation

More general terms

• mitochondrial membrane protein
• carrier protein (transporter)

More specific terms

• mitochondrial brown fat uncoupling protein 1; UCP 1; thermogenin (UCP1, SLC25A7)
• mitochondrial uncoupling protein 2; UCP 2; UCPH (UCP2 SLC25A8)
• mitochondrial uncoupling protein 3; UCP 3 (UCP3 SLC25A9)
• mitochondrial uncoupling protein 4; UCP 4; solute carrier family 25 member 27 (SLC25A27, UCP4, UNQ772/PRO1566)