carboxypeptidase-N, plasma carboxypeptidase-B, kininase-1, anaphylatoxin inactivator or arginine carboxypeptidase

Function

• protective against potent vasoactive & inflammatory peptides containing C-terminal Arg or Lys (kinins or anaphylatoxins) which are released into the circulation

Cofactor: binds 1 Zn+2 per subunit (putative)

Structure

• tetramer of two catalytic chains & two glycosylated inactive chains

Compartment

secreted, extracellular space

Expression

plasma

More general terms

• multisubunit protein
• carboxypeptidase
• metalloprotease
• secreted protein

Database

• OMIM: https://mirror.omim.org/entry/212070