CD302 (C-type lectin domain family 13 member A, C-type lectin BIMLEC, type 1 transmembrane C-type lectin receptor DCL-1, CLEC13A, DCL1, KIAA0022)
Jump to navigation
Jump to search
Structure
contains 1 C-type lectin domain
Compartment
membrane
Alternative splicing
named isoforms=3
Expression
- expressed in myeloid & B lymphoid cell lines
Pathology
- isoforms 2 & 3 are expressed in malignant Hodgkin's lymphoma Reed-Sternberg cells by a transcriptional control mechanism which cotranscribe an mRNA containing LY75 & CD302 prior to generating the intergenically spliced mRNA to produce LY75/CD302 fusion proteins