cyclin-dependent kinase inhibitor 2B-related protein; p15INK4B-related protein (P15RS, RPRD1A)

Function

• may act as a negative regulator of cyclin D1 (CCND1) & cyclin E (CCNE1) in the cell cycle

Structure

• belongs to the UPF0400 (RTT103) family
• contains 1 RPR domain

Alternative splicing

named isoforms=3

Expression

up-regulated in cells overexpressing CDKN2B

More general terms

• cyclin-dependent kinase inhibitor (CDKI, CDKN)
• other protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96P16.html