CC chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; MIP-3 beta receptor; EBV-induced G-protein coupled receptor 1; EBI1; BLR2; CDw197; CD197 (CCR7, CMKBR7, EBI1, EVI1)
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Function
- receptor for the MIP-3-beta chemokine
- probable mediator of normal lymphocyte functions
Structure
belongs to the G-protein coupled receptor 1 family
Compartment
Expression
- expressed in various lymphoid tissues & activated B-cells & T-cells
Pathology
- probable mediator of EBV effects on B-lymphocytes
- up-regulated in B-cells infected with Epstein-Barr virus & T-cells infected with Herpesvirus 6 or 7
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P32248.html
- ↑ Wikipedia; CC chemokine receptors entry http://en.wikipedia.org/wiki/CC_chemokine_receptors