CD53; leukocyte surface antigen CD53; cell surface glycoprotein CD53; tetraspanin-25; Tspan-25 (MOX44, TSPAN25)

Function

• may be involved in growth regulation in hematopoietic cells

Structure

belongs to the tetraspanin (TM4SF) family

Compartment

membrane

Expression

• pan-leukocyte marker
• B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes & peripheral T-cells
• platelets, red blood cells & non-hematopoietic cells stain negatively with antibody

More general terms

• tetraspanin (transmembrane-4-superprotein)
• CD antigen
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:963
• OMIM: https://mirror.omim.org/entry/151525
• UniProt: http://www.uniprot.org/uniprot/P19397.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=963