CD156; cell surface antigen MS2; a disintegrin & metalloproteinase domain 8 (ADAM8)

Function

role in extravasation of leukocytes (putative)

Cofactor: binds 1 Zn+2 per subunit (probable)

Structure

• contains 1 disintegrin domain
• contains 1 EGF-like domain
• contains 1 peptidase M12B domain

Compartment

plasma membrane

Expression

expressed on neutrophils & monocytes

More general terms

• CD antigen
• ADAM protease

Database

• UniProt: http://www.uniprot.org/uniprot/P78325.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=101
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:101
• OMIM: https://mirror.omim.org/entry/602267