disintegrin domain

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Introduction

Domain of about 70 amino acid residues present in disintegrins, thought to interact with the glycoprotein IIb-IIIa complex & inhibit platelet aggretation. The disintegrin domain contains an Arg-Gly-Asp (RGD) sequence, a recognition site of many adhesion proteins.

More general terms

Additional terms

References

  1. prosite :accession PS00427