viral Group-specific AntiGen [GAG] protein
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Introduction
Precursor cleaved to yield capsid proteins. (Group-specific AntiGen ==> GAG)
Contains: Matrix protein p17 (MA) Capsid protein p24 (CA) Spacer peptide p2 Nucleocapsid protein p7 (NC) Spacer peptide p1; p6-gag]
Function
- orchestrated tasks during assembly, budding, maturation, infection stages of the viral replication cycle
- during viral assembly, the proteins form membrane associations & self-associations that ultimately result in budding of an immature virion from the infected cell
- during viral assembly to selectively binds & packages 2 plus strands of genomic RNA
- endogenous Gag proteins may have kept, lost or modified their original function during evolution.
More general terms
More specific terms
Additional terms
References
- ↑ Watson et al Molecular Biology of the Gene, Benjamin Cummings, Menlo Park, CA 1987, pg 937
Database
- UniProt: http://www.uniprot.org/uniprot/O41798.html
- UniProt: http://www.uniprot.org/uniprot/P87889.html
- UniProt: http://www.uniprot.org/uniprot/O12157.html
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