D-aspartate oxidase (DASOX, DDO)

Function

• selectively catalyzes oxidative deamination of D-aspartate & its N-methylated derivative, N-methyl D-aspartate

D-aspartate + H2O + O2 <--> oxaloacetate + NH3 + H2O2

Cofactor: FAD or 6-hydroxyflavin adenine dinucleotide

Structure

• belongs to the DAMOX/DASOX family

Compartment

peroxisome

Alternative splicing

named isoforms=2

More general terms

• flavoprotein
• oxidoreductase

Database

• OMIM: https://mirror.omim.org/entry/124450
• UniProt: http://www.uniprot.org/uniprot/Q99489.html