gamma-glutamyltranspeptidase 3 (gamma-glutamyltransferase 3) [contains: gamma-glutamyltranspeptidase 3 heavy chain; gamma-glutamyltranspeptidase 3 light chain] (GGT3P GGT3)

Function

• initiates extracellular glutathione (GSH) breakdown
• catalyzes transfer of the glutamyl moiety of glutathione to amino acids & dipeptide acceptors (putative)
• sulfur metabolism; glutathione metabolism

(5-L-glutamyl)-peptide + an amino acid <--> peptide + 5-L-glutamyl amino acid

Structure

belongs to the gamma-glutamyltransferase family

Compartment

membrane

Genetics

could be the product of a pseudogene

More general terms

• enzyme
• glycoprotein
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/A6NGU5.html