kaptin (actin-associated protein 2E4, KPTN)
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Function
- may be involved in actin dynamics
- may play a role in producing the sensory apparatus in hair cells
- may play a role in actin rearrangements that accompany platelet activation & stereocilia formation
- associates with one end of F-actin filaments
Compartment
- cytoplasm, perinuclear region, cell projection, stereocilium, growth cone
- perinuclear at the tips of stereocilium in the inner ear
- localized at sites of actin polymerization in motile f fibroblasts & neuronal growth cones