cytoskeleton-associated protein 5 (colonic & hepatic tumor over-expressed protein, Ch-TOG protein, CKAP5, KIAA0097)

Function

• plays a major role in organizing spindle poles
• interacts with TACC1

Structure

• belongs to the TOG/XMAP215 family
• contains 9 HEAT repeats

Expression

• expressed in skeletal muscle, brain, heart, placenta, lung, liver, kidney, pancrea

Pathology

over-expressed in hepatomas & colonic tumors

More general terms

• cytoskeletal protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q14008.html