actin-like protein 6B; 53 kD BRG1-associated factor B; actin-related protein Baf53b; ArpNalpha; BRG1-associated factor 53B; BAF53B (ACTL6B, ACTL6, BAF53B)

Function

• component of the brain-specific chromatin remodeling complex (bBAF complex)
• component of the neuron-specific chromatin remodeling complex (nBAF complex)
• required for postmitotic neural development & dendritic outgrowth
• ACTL6B is not essential for assembly of the nBAF complex but is required for targeting the complex & CREST to the promoter of genes essential for dendritic growth

Structure

belongs to the actin family

Compartment

nucleus

More general terms

• cytoskeletal protein
• nuclear protein

Additional terms

• actin-related protein 6; hArp6; hARPX (ACTR6, CDA12)

Component of

• bBAF complex (brain-specific chromatin remodeling complex)
• nBAF complex (neuron-specific chromatin remodeling complex)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51412
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51412
• OMIM: https://mirror.omim.org/entry/612458
• UniProt: http://www.uniprot.org/uniprot/O94805.html