growth arrest-specific protein 7; GAS-7 (GAS7 KIAA0394)

Function

• may play a role in promoting maturation & morphological differentiation of cerebellar neurons

Structure

• contains 1 FCH domain
• contains 1 SH3 domain
• contains 1 WW domain

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=3

Pathology

• chromosomal translocation t(11;17)(q23;p13) involving GAS7 with MLL/HRX is a cause of acute myeloid leukemia

More general terms

• proto oncogene protein
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8522
• OMIM: https://mirror.omim.org/entry/603127
• UniProt: http://www.uniprot.org/uniprot/O60861.html