heterogeneous nuclear ribonucleoprotein H3; hnRNP H3; heterogeneous nuclear ribonucleoprotein 2H9; hnRNP 2H9 (HNRNPH3, HNRPH3)

Function

• role in RNA splicing
• participates in early heat shock-induced RNA splicing arrest
• different isoforms may possess different RNA splicing functions

Structure

• great structural variations in different isoforms
• contains 2 RRM domain (RNA recognition motif)s

Compartment

nucleus

Alternative splicing

named isoforms=6

More general terms

• heterogeneous nuclear ribonucleoprotein (hnRNP)
• RNA-binding protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3189
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3189
• OMIM: https://mirror.omim.org/entry/602324
• UniProt: http://www.uniprot.org/uniprot/P31942.html