nucleolysin TIAR; TIA-1-related protein (TIAL1)

Function

• RNA-binding protein
• possesses nucleolytic activity against cytotoxic lymphocyte target cells
• may be involved in apoptosis

Structure

contains 3 RRM domain (RNA recognition motif)s

Compartment

• cytoplasmic granule.
• cytoplasmic granules of cytolytic T-lymphocytes

More general terms

• RNA-binding protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q01085.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7073
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7073
• OMIM: https://mirror.omim.org/entry/603413